Everybody loves cats. They are the sweetest creatures ever in the nature. When they purr, there is no person in the room left nervous. But, in this case, there is one man who is more after what cats are about to inherit, instead of cats themselves. The story begins with getting to know a gorgeous Parisian cat family, Duchess and her three most adorable kittens- Berlioz, Toulouse and Marie. Berlioz is a gifted pianist, Toulouse is a painter and Marie is simply an adorable singer. They are taken care of by a lady called madame Adelaide Bonfamille, who is in retirement and they are the joy of her life. As she has lots of money and is about to leave all to the cats, jealous and greedy butler Edgar is looking to get rid of them and inherit all himself. As he manages to kidnap them and leave them somewhere outside of the city, these house cats are going to have to find a way to get back home. Luckily for them, a stray cat called Thomas O'Malley is there to help them. At first, he hopes to get something out of that, but as the time goes by, he gets drawn to this family of house cats, falls in love with Duchess and her kids as well. As they get on the journey back home, they go through various adventures.